Relationship between AZFc deletions and testicular histology in infertile South Chinese men with azoospermia and severe oligospermia
نویسندگان
چکیده
منابع مشابه
Relationship between AZFc deletions and testicular histology in infertile South Chinese men with azoospermia and severe oligospermia
BACKGROUND The AZFc deletion has been associated with wide range of phenotypes including complete absence of germ cells in the testes (SCOS), reduction in germ cells hypospermatogenesis, and maturation arrest. The main objective of this study was to evaluate the relationship between AZFc microdeletions and testicular histology in South Chinese men with azoospermia or severe oligospermia. FIND...
متن کاملThe Prevalence of Y Chromosome Microdeletions in Iranian Infertile Men with Azoospermia and Severe Oligospermia
OBJECTIVE Microdeletions of the Y chromosome long arm are the most common molecular genetic causes of severe infertility in men. They affect three regions including azoospermia factors (AZFa, AZFb and AZFc), which contain various genes involved in spermatogenesis. The aim of the present study was to reveal the patterns of Y chromosome microdeletions in Iranian infertile men referred to Royan In...
متن کاملthe prevalence of y chromosome microdeletions in iranian infertile men with azoospermia and severe oligospermia
objective: microdeletions of the y chromosome long arm are the most common molecular genetic causes of severe infertility in men. they affect three regions including azoospermia factors (azfa, azfb and azfc), which contain various genes involved in spermatogenesis. the aim of the present study was to reveal the patterns of y chromosome microdeletions in iranian infertile men referred to royan i...
متن کاملPartial AZFc deletions in infertile men with cryptorchidism.
BACKGROUND A specific type of partial AZFc deletion, called 'gr/gr' deletion, was recently proposed as genetic risk factor for spermatogenic impairment and testis cancer. Since both pathologies can be part of the testicular dysgenesis syndrome (TDS), we aimed to define the role of 'gr/gr' deletion in the aethiopathogenesis of another component of the TDS: cryptorchidism. METHODS A total of 14...
متن کاملO-1: Evaluation of Ethnic Patterns of Y Chromosome Microdeletions in Iranian Infertile Men with Azoospermia/Severe Oligospermia Referred to Royan Institute
Background: Microdeletions of the long arm of the chromosome Y are the most common molecular genetic cause of severe infertility in men which affect three regions of AZFa, AZFb and AZFc (Azoospermia factor). These regions contain various genes involved in spermatogenesis. The effect of ethnicity on the patterns of Y chromosome microdeletions has not been extensively studied, particulary in Iran...
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ژورنال
عنوان ژورنال: SpringerPlus
سال: 2016
ISSN: 2193-1801
DOI: 10.1186/s40064-016-3512-7